Improving Quantitative Trait Loci Mapping Resolution in Experimental Crosses by the Use of Genotypically Selected Samples

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Improving quantitative trait loci mapping resolution in experimental crosses by the use of genotypically selected samples.

One of the key factors contributing to the success of a quantitative trait locus (QTL) mapping experiment is the precision with which QTL positions can be estimated. We show, using simulations, that QTL mapping precision for an experimental cross can be increased by the use of a genotypically selected sample of individuals rather than an unselected sample of the same size. Selection is performe...

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ژورنال

عنوان ژورنال: Genetics

سال: 2005

ISSN: 1943-2631

DOI: 10.1534/genetics.104.033746